Pharmaceutical Companies and How Their Health Information is Managed Through Clinical Trials Essay

Clinical Trials are critical to how pharmaceutical companies manage health information. Through the years the Federal Drug Administration saw many problems with the use of clinical trials and worked at fixing them. Regulations and guidance was put into place to ensure that sponsors of clinical trials; medical researchers, ethic committees and pharmaceuticals understand how they can efficiently carry out the trials while complying with federal law. Pharmaceutical companies rely heavily on these trials to determine how the health information gained is used for research and marketing on a variety of levels within the company including their main purpose of drug development. The clinical trial is an investigational product in human volunteers to examine effects from experimental drugs, medical device, or biologic, such as a vaccine, blood product, or gene therapy (Bren, 2007, 23). The main problem of many clinical trials in the past was the possibility of bias. Meaning any factor that distorts the true outcome of a study, that leads to overestimating or even underestimating the effect of a drug that was being investigated. But now with better FDA regulations stricter guidelines help to prevent this type of bias. When a pharmaceutical has a drug to market it must first submit an application to the FDA that shows data from controlled clinical trials. FDA then reviews the application to make a decision on whether the clinical trials are well-control or if they show the effectiveness of the product. It must also show that all available data show that the product is safe enough to allow it on the public market. Before 1938 pharmaceutical companies could market a drug without submitting any information to the FDA or for that fact any agency. â€Å"The Federal Food, Drug, and Cosmetic Act (FD&C Act) of 1938 was passed when over 100 children died from taking a sulfa drug that had not been tested in humans† (Bren, 2007, 24). The FDA adopted the standard, after this incident, that the benefits of a product outweigh the risks. In 1962 new law created made pharmaceuticals responsible to prove that their drugs were both effective and safe if they wanted to market them to the public. Making clinical trial more efficient was needed. In an article â€Å"The Advancement of Controlled Clinical trials† Bren discusses the future of clinical trials in which the FDA see a future of improving clinical trials by standardizing and automating trial procedures, conduct and data processing. Another addition to the trials would be to use patient reported outcomes. â€Å"For systematic diseases, what really matters is how you feel, not how the doctor feels about you† (Bren, 2007, 28). Another important advancement in managing pharmaceutical companies is how they manufacture and the distribution of medication. This was called the Critical Path Initiative. This focuses on the path which medical products must travel from development to patients. The Critical Path Initiative is FDA’s effort to stimulate and facilitate a national effort to modernize the sciences through which FDA regulated products are developed, evaluated, and manufactured† (Bons, Aubert & Bonnely, 2000). Pharmaceutical companies had already recognized that there were weaknesses that needed improvement in clinical trials and that some could be easily improved while others would need a different type of organization, but in general that none of them were really difficult to address. Choosing an independent institute for conducting surveys and trial would give them an opportunity for impartial opinions in clinical trials. Human subjects is an important key in clinical development and investigators are the spokesperson for that study so improving investigator participation in clinical trials would help to improve subject participation and the quality of the whole trial. So looking at the clinical trial in itself would be how pharmaceutical manage the health inf

Investigation into Roles and Contracts of the Music Industry Essay

Scenario Your local paper has assigned you with a task to present them with information about the roles and contracts in the Music industry. Carry out an investigation that describes/explains/comments critically on the roles and contracts of one area of the Music Industry and deliver your results as a presentation to the class. Task 1: Using Publisher/ Word, you need to research, write and describe the contracts associated with an area of the Music Industry (Live Performance: e.g. artist’s responsibilities with a label, or a manager/agency’s responsibilities with an artist/performer) (P3) In order to gain a MERIT grade, in addition to the requirements of the PASS criteria, you will need to describe and explain the above by providing examples. (P1, P2, M1, M2) In order to gain a DISTINCTION grade, in addition to the PASS and MERIT criteria, you will need to describe, explain and comment critically the above by giving examples, drawing conclusions from experience and/or research (P1, P2, M1, M2, D1, D2) 2 Know the professional roles within a chosen area of the music industry Live performance: eg performer/artist, DJ, agent, promoter, venues and stage management, crew/ technicians, security, merchandise Record companies: eg A&R, promotion, distribution and retail, merchandising Music publishing companies: eg publishing, copyright, sales, composer and artist development  Artist management: eg artists, songwriter/composer, manager Assessment Method: Class presentation. To include referencing

Steryotypes Of Teenagers

I am writing to inform you about how I feel when I see certain articles that have been published in your newspaper. Most of these articles are about teenagers with a lot of negative coverage. I hope through this letter that you will understand what so many teenagers feel when reading the negative articles that YOU publish. Hopefully, after this letter you won’t ever stereotype anyone without full information about them again. It was just last week that I was reading a copy of ‘The Sun’ when my eyes focussed on this one article, it was titled ‘Jeremy’s ‘Happy Slap’ Ordeal’.My eye then alighted on Jeremy Clarkson’s face, (the guy from Top Gear) and that I think just spurred me on to read more. I didn’t really know what to expect but honestly I had no idea this was about teenagers. Whilst reading this article I realized something was wrong. Usually when you have an article like this in the newspapers there’s alway s two points of view. Normally the two parties or persons involved have a say, but this particular article shows extreme bias.We simply hear Jeremy’s point of view and leave the teenagers opinions unheard. Personally I think this is very unfair, when journalists do things like this, it’s not right; it’s actually very sly and manipulative. You instantly portray Clarkson as ‘our man†¦ the victim’ and the others as ‘a gang of teenage thugs’. How are reader’s going to have a balanced view of the situation, when this is how you set the article up? There is one quote in the article about police which I am angry about, which is â€Å"the police?Oh come on they are too busy filling in health and safety forms and processing speeding fines†. This quote irritates me dramatically because frankly it’s not true. The, I see them police are not too busy with speeding fines or health and safety forms. I always see police when I go out dealing with young drunk men or people brawling in the street. This tells me that Jeremy was wrong about the police. Jeremy Clarkson has obviously been brainwashed by the media.He’s just making assumptions about stuff, like most famous people do, because unlike some people he doesn’t have the decency to go and talk to teenagers and find out the truth, or maybe there aren’t any brains in his head. Either that or HIS parents didn’t bring him up properly. His parents probably didn’t teach him basic manners and he doesn’t know what being polite is. Interestingly enough, as I was reading on I noticed how conceited and arrogant he was when discussing the parenting skills of these teenagers.Jeremy states that ‘Nothing can be done about the parents because they are too thick’. Yes, he is attempting to be humorous, but there is truth, in his eyes, in what he is saying and it is offensive! I strongly disagree with him because pare nts have the intelligence to do anything for their kids and help them through their lives. I was actually very enraged at this, I can tell you that my parents are NOT and I repeat NOT thick. Rather they are very intelligent because to raise a baby into a grown female/male with basic manners and high morals takes a lot.I can understand why he is thinking like this because he didn’t have a very happy ending of the encounter with the teens but common who needs all of the aggression? He starts off by branding teenagers as brutal thugs who love drink a lot of cider and love to stab passers-by. When i read this i feel really outraged that he has the audacity to say such things, I mean how the hell does he know all teenagers are like this. I can confirm to you that i am a teenager and me and my friends don’t drink vast quantities of alcohol or love to stab passers-by as a hobby.I have to say he is being really ignorant because he’s trying to make teenagers look all vio lent and what’s really weird is that the teens didn’t touch him but he just thought he’d just grab the ringleader by the scruff of his neck. Now what do you call that? I say that’s what you would call a ‘middle age thug’. Now there is no way you can disagree with me he was the aggressor there, he just assumed it was ok to enforce violence on a group of teens who hadn’t even touched him.

A Glimpse of the Japanese Era through Filipino Paintings Essay

I.1 Background in the selection of the topic and AV Media to use. In Philippine history, many countries had tried to own the lands from when the time Spaniards first stepped in to the time of World War II where the country was invaded by Japanese army. Because of the invasions and wars, many Filipino people sacrificed their lives for freedom and democracy. Just like the national hero, Dr. Jose Rizal who sacrificed his life to awaken people’s patriotism, many artists also made artworks to express their feelings on how the natives were treated back then. Flash card, from the term itself, is a card used to display something including words and even images for pictorial cards just like posters. They are simple, cheap, versatile, yet often underexploited resources. Using them is a great way to present topics that include images and other visual symbols. With the aid of flash cards as instructional module, audience could learn better, understand and remember about the life of the Filipino people under the Japanese administration through some of the paintings made by Filipino painters. I.2 Importance and Significance of the chosen topic and the AV Media to use At present, the rise of new artworks is noticeable worldwide. Sometimes, artworks of the earlier times are neglected and forgotten, thus this topic is chosen to have a glimpse of our past and look back on the happenings that leaved significant marks in our history. This topic would also help the present generation recall about the country’s historical events and create a sense of nationalism to fight for freedom. Topics on artworks such as in the field of painting should at least include visual media to enhance discussion and keep the interest of the audience. The use of flash cards with printed image of the actual paintings on the Japanese occupation could help audience visualize, learn more and understand better the life of the people and the condition of the country back then. On the side of the lecturer, he doesn’t have to spend too much since he can create his own sets of flash cards for his specific needs. IIOBJECTIVES. II.1 General Objective To describe the art of painting that reflects the condition of the country during the Japanese times II.2 Specific Objectives To describe the nature of the paintings of the Japanese era and the styles used by the painters To discuss the purpose or intention of the painters and what message they want to convey in making their artwork III.DISCUSSION III.1 Review of Literature of the chosen Topic and AV Media Chosen From one colonizer to another–after more than three centuries of Spanish rule, the Americans came and then the Japanese to enslave our country. In response to the Japanese propaganda, according to Dr. Alice G. Guillermo, Filipino painters reacted by producing the following works: †¢ paintings that may be implicitly supportive of the Japanese occupation such as Vicente Alvarez Dizon’s â€Å"A Day Begins† done in 1942 †¢ genre scenes that seem neutral such as Crispin V. Lopez’s â€Å"Baguio Market† made in 1943 showing Japanese soldiers interacting with women vegetable vendors †¢ paintings that bring out national identity such as Emilio G. Santiago’s â€Å"Christmas Eve† made in 1942 which shows a traditional Filipino scene that evokes nostalgia †¢ paintings alluding to the social conditions of the time such as Pilar M. Santiago’s â€Å"Evacuees† made in 1941,Irineo Miranda’s Home from Work made in 1944, and Simon Saulog’s Conspiracy made in 1943 which shows a group of men in an evening meeting which suggests to the underground anti-Japanese movement. A suspension on artistic activity was prevalent during the Japanese occupation. However, some visual artists still managed to produce artworks based on the atrocities brought by the war. Artists represented in the collection: Dominador Castaà ±eda, Demetrio Diego, Diosdado Lorenzo, Romeo Tabuena, Gene Cabrera and others. In the field of painting, the most disturbing and the largest is Diosdado Lorenzo’s â€Å"Rape and Massacre in Ermita†. Lorenzo’s painting portraying two Japanese soldiers raping and killing family members in an Ermita home depicted a common horror not just in Manila neighborhoods but throughout many parts of the country. A young girl in the foreground is already dead from stab wounds, while another young girl with long hair in the background is naked and wounded. The husband has just been bayoneted. The wife struggling with a Japanese soldier clutching a knife, her breasts exposed, is about to be raped and murdered. A crying baby in a crib is a foreboding sign. There were countless stories by World War II survivors who saw Japanese soldiers flinging babies into the air and thrusting them with bayonets as they fell to earth. An altar with dangling rosaries is set on one side, mute and helpless. Tropical foliage seen from an open window vainly hides the fire and terror occurring outside. Dominador Castaneda’s work, entitled â€Å"Doomed Family† is of a different intensity but harrowing as well. Done in 1945, this oil on canvas has the feel of a silent scream. A mother lays dead; her long hair on the floor simulates blood. A lifeless father is bound in rope, his bloodied back mercilessly whipped. A child, still alive and tied, has her mouth open emitting perhaps a frightened helpless wail. One cannot tell if they are depicted in a home or in a cell. Their doom in the dark is the only certainty. A third painting related to World War II is entitled â€Å"Capas† by Demetrio Diego, a distinguished painter and former chief artist for the Sunday Times Magazine. It depicts the slow and agonizing death of Filipino prisoners-of-war in a Tarlac internment camp. The prisoner in the center seems to check on his companion’s condition beside him. The act is noble but futile. A man seated at the foot of the bamboo bed is malnourished and ready to die. Another famous Filipino historical and war painter is Fernando Amorsolo y Cueto. He is known as â€Å"The Painter of Philippine Sunlight† because his works capture the brilliance of the Philippine sun. He paints from within the Filipino values, character and soul. The artistic trademark of Amorsolo and his greatest contribution to Philippine painting is the backlighting technique. In a typical Amorsolo painting, figures are outlined against a characteristic glow, and intense light on one part of the canvas highlights nearby details. Portrayals of human sorrow and suffering were revealed through his illustrations of â€Å"women mourning their dead husbands, files of people with pushcarts and makeshift bags leaving a dark burning city tinged with red from fire and blood†. One particular painting, the Defense of a Filipina Woman’s Honor (1945), had two figures huddled in a corner: a man defiantly about to defend his wife or daughter from being raped or executed by an invisible Japanese soldier. The Japanese soldier is outside Amorsolo’s canvas, but from the defiant look of the man, it can be assumed that the intruder is still inside the house. This painting represented his unspoken defiance against oppression. There are several ways of presenting the topic—one of which is the use of flash cards especially for the images of the paintings which portrays the happenings in the Philippine history. Though there are other better ways of presenting it such as through PowerPoint, flash cards are more applicable especially when there is no access to computer for the operation, and they can also be used as back-up modules if ever there is power failure during the PowerPoint presentation. Flash cards are handy and cheaper compared to other AV media. The thing that matters most when using flash cards is that they should be of the same sizes that are visible to a certain size of audience. III.2 Materials and Procedure in the Preparation of the AV Media The materials needed in the discussion are: cards (folder size) to be used as flash cards, printed photos or images of the paintings, and glue to mount the printed images on the cards. The first step in the production of the AV media is choosing an interesting topic that is applicable for the chosen media. Researching for related literature follows and summarizing the content of the research by choosing the most important details for the presentation. Next is to have printed image of the paintings included in the research made and mounting them to the folder-size cards. The last thing to do is to practice for the presentation and proper use of the media chosen. III.3 Application of the AV Media The flash cards will be used in presenting the paintings made by the Filipino painters on the Japanese occupation. They will also be used to present important facts such as the title of the paintings, names of the painters and a little detail of the paintings shown. This will help audience to get familiar with the artworks, remember who painted them and what the paintings were implying. III.4 Sample Test/ Evaluation questions 1. Who are some of the Filipino painters who made paintings about the Japanese period in the country? 2. What common message do their paintings convey? 3. What are the media used by these painters in creating their pieces? 4. What is the name of the Dominador Castaneda’s painting? 5. What happened to the artistic activities during the Japanese occupation? 6. Who was called as â€Å"the Painter of the Philippine Sunlight?† 7. What was Amosrolo’s biggest contribution to the Philippine painting? 8. Who was the painter of the â€Å"Rape and Massacre in Ermita†? 9. How was the life of Filipinos during Japanese occupation? 10. What does â€Å"Capas† by Demetrio Diego depicts? IVCONCLUSION In the Philippines, almost all fields of art and our history have connections to other countries. The culture that the Filipinos have at present was influenced by the foreign countries that once colonized the Philippines. For the four years of the Japanese occupation, from 1941 to 1945, the colonizers, as a means of propaganda, used the visual arts. They produced posters, leaflets, flyers, comics, and illustrations that were dropped from passing airplanes. These included colored drawings, watercolor, photographs, photomontages, or calendar illustrations. The sixties and the seventies became a period of experimentation and exploration of new media, techniques, styles, forms of expression, and concepts in art. It also marked the increased consciousness of visual artists to bring their art closer to the people through forms like murals, prints, and cartoons. Paintings, for example, were one of the artworks that the Filipino people used in expressing their feelings to awaken patriotism of their countrymen. V.SUMMARY. In Philippine history, many countries had tried to own the lands from when the time Spaniards first stepped in to the time of World War II where the country was invaded by Japanese army. Because of the invasions and wars, many Filipino people sacrificed their lives for freedom and democracy. Just like the national hero, Dr. Jose Rizal who sacrificed his life to awaken people’s patriotism, many artists also made artworks to express their feelings on how the natives were treated back then. At present, the rise of new artworks is noticeable worldwide. Sometimes, artworks of the earlier times are neglected and forgotten, thus this topic is chosen to have a glimpse of our past and look back on the happenings that leaved significant marks in our history. The general objective of this module is to describe the art of painting that reflects the condition of the country during the Japanese times. Specific objectives are: to describe the nature of the paintings of the Japanese era and the styles used by the painters; and to discuss the purpose or intention of the painters and what message they want to convey in making their artwork. There are several ways of presenting the topic—one of which is the use of flash cards especially for the images of the paintings which portrays the happenings in the Philippine history. Though there are other better ways of presenting it such as through PowerPoint, flash cards are more applicable especially when there is no access to computer for the operation, and they can also be used as back-up modules if ever there is power failure during the PowerPoint presentation. The flash cards will be used in presenting the paintings made by the Filipino painters on the Japanese occupation. They will also be used to present important facts such as the title of the paintings, names of the painters and a little detail of the paintings shown. This will help audience to get familiar with the artworks, remember who painted them and what the paintings were implying. For the four years of the Japanese occupation, from 1941 to 1945, the colonizers, as a means of propaganda, used the visual arts. The sixties and the seventies became a period of experimentation and exploration of new media, techniques, styles, forms of expression, and concepts in art. It also marked the increased consciousness of visual artists to bring their art closer to the people through forms like murals, prints, and cartoons. Paintings, for example, were one of the artworks that .the Filipino people used in expressing their feelings to awaken patriotism of their countrymen. VI.REFERENCES Silva, John L. March 4, 2007. â€Å"Paintings To Remind Us Of Japanese Cruelties In World. War II†.John’s Thoughts And Deeds. Hernandez, Eloisa May P. â€Å"The American and Contemporary Traditions in Philippine Visual Arts†. National Commission for Culture and the Arts. Salvio, Ma. Czarina Colleen C. September 2011. â€Å"Philippine Art Paintings†. When my Life Begins. http://colleensalvio.blogspot.com/2011/09/philippine-art-paintings.html http://littleprincess1.hubpages.com/hub/The-Controversial-Painting http://en.wikipilipinas.org/index.php?title=Fernando_Amorsolo#Historical_and_War_ Paintings Killkathari. February 2013. B’s LOG 5. http://www.teachingenglish.org.uk/articles/using-flash-cards-young-learners.

Understanding Practical Business and Organizational Research Assignment

Understanding Practical Business and Organizational Research - Assignment Example The study elucidates the huge problem of poor performance, accountability, and transparency in the government institutions such as municipalities. The Americans have expressed their dissatisfaction of the delivery of services in the government institutions. On the other hand, the purpose of the study was to evaluate the contribution of performance measure to the sustainable improvement, accountability, and transparency of the government organization (Sanger, 2012). The research hypothesized that cities that had sophisticated performance measurement systems would have a high likelihood of using the performance data to improve performance. However, the research did not have research questions. The study used an analytic approach to collect quantitative data from a sample of 190 cities. The researchers searched the cities with a high likelihood of measuring performance with the intent of improving service delivery (Sanger, 2012). Fundamentally, the researchers selected a sample from four service areas namely police, parks and recreation, fire, and public works. The study used quantitative approaches to analyze the data and present it in tables. The study findings are important for the city mayors and officials who hold leadership positions to implement the information gotten from performance measurement for the betterment of services. In summary, the researchers established that government institutions rarely implement the information from performance measurements for the improvement of services. The data analysis indicates that few organizations use the information to improve service delivery. The analytic approach used in this study can be applied to solve performance problems. The researchers have analyzed the problem by seeking the primary data of the various cities. Primary data establishes the main cause of a problem, and thus provides a platform for selecting the best solution (Zikmund, 2013). For

Human Resource Management Essay Example | Topics and Well Written Essays - 1750 words - 2

Human Resource Management - Essay Example Also, a conclusion will be provided in the last section of the paper. 2. The Report Free Malaysia Today’s news report last March 4, 2013 by one of its staff James Pereira has delineated that Malaysian businesses are devoted to stipulate customers with a great service. However, Pereira inscribes that these employees are notably in minority clusters. He insists that for a firm to be recognized internationally, it must be inculcated with employees who are haunted with customer satisfaction. There is indeed a right approach to having an exceptional divergent type of employees, and for this panorama to be feasible, a scientific facet must be on hand. As such, a business to be dubbed as a predominant venture and become a successful world-class firm, it must be infused with a top-flight reputation, which can only be achieved through employees. The top-flight reputation runs the profitable aspects of a firm and the formula to attain this is: â€Å"Right Employee x Right Training x Ri ght Performance x Right Reward = Right Profits† (Pereira, 2013). Notably, having been depicted as a formula of accumulating right profits, the latter is deemed as a paragon that becoming successful is infused with a scientific aspect. 3. Performance Management Right profits are quantified by four aspects, which include right performance (Pereira, 2013); therefore, performance should be managed well leading it to become right. Performance management can be perceived in a broad or narrow context. In the broader context, the administration will be viewed in the conduct of assessing the organizational performance--the measurement and evaluation of the administration of a firm (Pantouvakis, 2011, p.13) --while in the narrow context, the assessment will be held in the performance of every employee. The first step to managing the performance is through role profiling--where employees can be coming from external staffing and internal passages, and thereby synergy must also be instille d (Storey, 2007, pp.274-276). Integrating these employees to work together and establishing the right culture of the organization can help sustain an effective synergy. The concept of integration is very significant because only in integration will rise the dominant aspect of synergy (Moulesong, 2013). Employees will perceive parity of value and unity of direction. They will somehow fathom that every entity in the organization has his or her certain role, and it matches a huge fraction or part of the measures that can assist in achieving the organizational goals effectively. In the light of synergy, employees can become more effective as they integrate them as they work individually (Tanriverdi, 2006, p. 59). The next salient thing the firm must do is to decide the measures, which should be perceived as a succinct set of information that measures the future standards or targets of the firm. Furthermore, setting the standards does not just depict expecting of what has to be done, but implementing what must be done. Diversification is a dominant aspect here since achieving one target cannot be attained with a one-sized-fits-all aspect of business. Otherwise stated, employee diversification can also assist effectiveness and efficiency of operations because one of the competitive advantages of a firm is to have a diversified personnel (Ravichandran, et al., 2009, p.233). Reviewing the performance

Anatomy, Physiology & Disease Assignment Example | Topics and Well Written Essays - 250 words

Anatomy, Physiology & Disease - Assignment Example A good example of communicable disease that poses a huge threat to public health include HIV/AIDS. This disease is easy to diagnose; the most common diagnosis is through blood tests. In essence, testing is done in order to identify the presence of antibodies created in the body in an effort to fight the HIV (Holland, Olsen and Florey, 2007). It is worth noting that the disease is caused by a virus known as Human immunodeficiency virus (HIV). Some of the signs and symptoms of HIV/AIDS according to Hall, Hall and Cockerell (2011) include weight loss, diarrhea, coughing, dermatitis, herpes, TB, unrelenting wounds, and abscesses. Prevention of HIV/AIDS depends on the mode of transmission. It can be transmitted through sexual intercourse, blood transfusion, and transmission from a pregnant mother to the unborn child. Prevention of the disease in relation to sexual transmission is achieved through the use of condoms and sex education. Blood ought to be screened thoroughly before transfusion to detect the presence of the disease. Pregnant mothers also ought to be tested and subsequent treatment given in case of presence of the disease (Ramaiah, 2008). Antiretroviral drugs are used to treat the disease. These drugs are taken on a daily basis in a bid to minimize the amount of the HIV virus in the body (Ramaiah, 2008). There are also post-exposure prophylaxis medications that are used for emergency treatments when an individual has been exposed to the virus (Hall, Hall and Cockerell, 2011). There is however no known cure for the disease. These medication are only used to reduce the amount of HIV in the body in order to allow the body fight infections. Epidemiological studies have proved that HIV is transmitted through three routes namely sexual transmission, exposure to contaminated blood, and mother to child transmission. The